This site is intended for healthcare professionals

Go to /sign-in page

You can view 5 more pages before signing in


Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

Authoring team

Bradykinin is a vasoactive nonapeptide produced by the kinin system. It has a number of tissue actions:

  • vasodilation, possibly by a direct effect and via prostaglandin mediation
  • increase in vascular permeability by the opening of intercellular gaps in post-capillary venules
  • stimulation of phospholipase A2 and production of arachidonic acid
  • slow-onset, long-duration contraction of smooth muscle
  • pain; again histamine mediation is likely

Physiologically, bradykinin may be important in:

  • regulating blood supply to exocrine glands
  • inflammatory responses
  • pain production of pancreatitis via kallikrein release

Bradykinin is inactivated by angiotensin converting enzyme.

Related pages

Create an account to add page annotations

Add information to this page that would be handy to have on hand during a consultation, such as a web address or phone number. This information will always be displayed when you visit this page

The content herein is provided for informational purposes and does not replace the need to apply professional clinical judgement when diagnosing or treating any medical condition. A licensed medical practitioner should be consulted for diagnosis and treatment of any and all medical conditions.


Copyright 2024 Oxbridge Solutions Limited, a subsidiary of OmniaMed Communications Limited. All rights reserved. Any distribution or duplication of the information contained herein is strictly prohibited. Oxbridge Solutions receives funding from advertising but maintains editorial independence.