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Hepatic disease in pre-eclampsia

Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

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Hepatocellular dysfunction leads to enzyme release, necrosis and swelling. This can cause epigastric pain, and, in extreme circumstances, rupture and exsanguination. Occasionally hepatic involvement in pre-eclampsia may lead to jaundice.

The clotting and hepatic problems together cause the HELLP syndrome: H : haemolysis, part of DIC from shredding on fibrin EL : elevated enzymes LP : low platelets


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