Craniosynostosis

Craniosynostosis is a condition where there is premature closure of the cranial sutures, resulting in deformity of the skull.

The condition may be primary or secondary; the former is the result of abnormal skull development, whereas the latter is the result of failure of brain growth. When referred to without prefix, primary craniosynostosis is usually implied.

• the main cause of craniosynostosis is premature closure of one or more cranial sutures (2)
  • usually occurs as an isolated condition, but may also be associated with other malformations as part of complex syndromes

Reference

1. Johnson D, Wilkie AO. Craniosynostosis. Eur J Hum Genet. 2011 Apr;19(4):369-76
2. Kajdic N, Spazzapan P, Velnar T. Craniosynostosis - Recognition, clinical characteristics, and treatment. Bosn J Basic Med Sci. 2018 May 20;18(2):110-116.