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Landau-Kleffner syndrome

Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

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Landau-Kleffner syndrome is a degenerative neurological disease of unknown aetiology seen in children between the ages of three and nine years.

The onset is rapid, with the development of:

  • aphasia, in the face of previously normal speech and language
  • seizures in 80% of patient, which can be focal or generalized

There is a typical EEG, with posterior temporal and parietal spike foci.

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