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Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

Authoring team

The indications for antiemetic therapy include:

  • motion sickness:
    • use hyoscine patches or antihistamines

  • drug-induced emesis:

  • gastric irritation:
    • common problem
    • take the offending drug with food, e.g. spironolactone
    • take frequent small doses

  • CNS irritation:
    • due to, e.g. opiates
    • treat with:
      • phenothiazines
      • metoclopramide

  • cytotoxic therapy

  • post-operative:
    • ensure that the anatomy is correct, e.g. do not start antiemesis if the patient is obstructed
    • drug therapy:
      • metoclopramide
      • phenothiazines

  • migraine:
    • i.v. metoclopramide promotes gastric emptying and so permits improved absorption of other therapies such as analgesics

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