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Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

Authoring team

  • mania:
    • in the acute phase
    • as prophylaxis for mania

  • lithium-augmentation of antidepressants:
    • lithium may be administered with tricyclic depressants in cases of resistant depression
    • failure to respond to lithium-augmented anti- depressants is an indication for ECT

  • prophylaxis in depression:
    • lithium is less effective in preventing recurrences of depression than in preventing episodes of bipolar affective disorder
    • maintenance therapy with a first-line antidepressant drug is usually preferable

  • lithium has been used in the treatment of premenstrual tension

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