Secondary depression
Secondary depression is a depressive episode that develops as a direct consequence of a pre-existing medical illness, substance use disorder, or another non-affective psychiatric condition.
Physical disorders include:
- malignancy
- hypothyroidism
- hyperparathyroidism
- Cushing's syndrome
- Addison's disease
- multiple sclerosis
- parkinsonism
- post-infection
- obstructive sleep apnoea
- chronic pain
- head injury
- stroke
- vitamin B12/folate deficiency
- HIV
Psychiatric disorders include:
- schizophrenia
- alcoholism
- dementia
- personality disorder
Drug-induced depression, including:
- corticosteroids
- interferons
- hormonal contraceptives
- anticonvulsants
- beta-blockers
- benzodiazepines
- isotretinoin
Reference
- NICE. Depression in adults with a chronic physical health problem: recognition and management. Clinical guideline CG91. Published October 2009
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