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Switching antidepressant (mirtazapine to moclobemide) in adults

Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

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Mirtazapine to moclobemide

Taper, washout and switch

  • gradually reduce the dose of mirtazapine and stop; wait 7 days before starting moclobemide

  • cross-tapering is not recommended due to the high risk of serotonin syndrome.

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