Last reviewed dd mmm yyyy. Last edited dd mmm yyyy
Switching antidepressant (tricyclic antidepressants (TCA) to monoamine oxidase inhibitors (MAOIs))
Switching to an MAOI is always a complex switch and you should follow specialist advice.
Taper, washout and switch with specialist advice
Cross-tapering is not recommended due to the high risk of serotonin syndrome.
From all except clomipramine and imipramine
From clomipramine or imipramine
Reference:
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