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Diffuse proliferative glomerulonephritis

Authoring team

Diffuse proliferative glomerulonephritis presents clinically with nephritic syndrome and is characterized by the following histological features:

  • mesangial and endothelial cell proliferation
  • polymorphonuclear cell infiltrate
  • granular subepithelial deposits of C3 and immunoglobulins
  • swollen glomeruli

Diffuse proliferative glomerulonephritis is caused by:

  • streptococcal infection
  • SLE

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