Radiation nephritis
This is an example of an interstial nephritis.
Acute radiation nephritis ccurs within 1 year of radiotherapy. Features include hypertension, anaemia, proteinuria and haematuria.
Chronic radiation nephritis:
- this may occur after acute radiation nephritis; alternatively chronic radiation nephritis may present with hypertension, anaemia, proteinuria or end-stage renal failure 2-5 years after radiotherapy treatment
Treatment:
- treatment of hypertension
- if end-stage renal therapy then renal replacement therapy e.g. haemodialysis
Prevention:
- during radiotherapy, ensure adequate shielding (or exclusion) of renal areas
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