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Thymoma and hypogammaglobulinaemia

Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

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These disorders may occur together in patients over 40 years of age. The patient has a mild hypogammaglobulinaemia but usually retains some IgA production.

Chronic and recurrent infections do not usually present a problem to these patients. The main difficulties arise from autoimmune phenomena such as neutropaenia, haemolytic anaemia, and sometimes myasthenia gravis.

The thymic tumour is often found on routine chest X-ray.

Surgical removal of the tumour is ineffective.

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