Risk factors for fracture in postmenopausal osteoporosis
As well as increasing age and low bone mineral density (BMD), many other factors can determine the risk of fracture.
Risk factors for fracture in postmenopausal osteoporosis
- Independent clinical risk factors for fracture:
- Parental history of hip fracture
- Alcohol intake of 4 or more units a day
- Prior fracture
- Rheumatoid arthritis (RA)
- Indicators of low BMD:
- Low body mass index (BMI) (<22kg/m2)
- Medical conditions e.g. ankylosing spondylitis, Crohn's disease, RA
- Conditions that result in prolonged immobility
- Untreated premature menopause
Reference:
- 1) NICE. Alendronate, etidronate, risedronate, raloxifene and strontium ranelate for the primary prevention of osteoporotic fragility fractures in postmenopausal women. Technology Appraisal 160. October 2008
- 2) NICE. Alendronate, etidronate, risedronate, raloxifene, strontium ranelate and teriparatide for the secondary prevention of osteoporotic fragility fractures in postmenopausal women. Technology Appraisal 161. October 2008
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