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Cholecystitis glandularis proliferans

Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

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In the literature, cholecystitis glandular proliferans is variously referred to as adenomyomatosis, adenomatous hyperplasia, and diverticulosis of the gallbladder.

It is a chronic inflammatory condition of the gallbladder wall, usually in the fundus. Histologically, inflammatory thickening of the mucosa causes sequestering of the epithelial crypts within the wall. A septum may form which separates the normal from the inflamed mucosa.

It may be a developmental abnormality or may be an acquired degenerative lesion. It is frequently asymptomatic but it may cause abdominal pain.

It is demonstrated by ultrasound or cholecystography. Treatment, when indicated, is by cholecystectomy.

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