Drug acetylation
Many drugs require acetylation for their metabolism. In the population there is a bimodal distribution in the rate of acetylation; the fast acetylation is autosomal dominant, and the slow is autosomal recessive.
Drugs which are significantly metabolised by acetylation include:
- isoniazid
- hydralazine
- procainamide
- phenelzine
- dapsone
- some sulphonamides
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