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Fibrinous inflammation

Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

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Fibrinous inflammation is a form of inflammation which is characterised by fibrin deposition. It may be acute, but more often it is a chronic response.

It results from the exudation of a high concentration of the plasma protein fraction. There is activation of the coagulation cascade and depostion of fibrin locally. Ultimately, organisation of the fibrin can occur with rigid fibrous tissue being laid down.

Body cavities and potential spaces are sites where fibrinous inflammation is more common e.g. the:

  • pericardial cavity, potentially resulting in restrictive fibrosis
  • pleural space
  • peritoneal cavity, potentially resulting in adhesions

It should be contrasted with serous inflammation.

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