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Risk factors

Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

Authoring team

The exact cause of gastroschisis is unknown.

The following have been reported to be associated with the development of the condition:

  • low maternal age
    • one European study found that compared with mothers aged 25-29, the relative risk was 7.0 (95% confidence interval 5.6 to 8.7) for mothers under 20 and 2.4 (2.0 to 3.0) for mothers aged 20-24 years.
  • use of illicit drugs - cocaine
  • early and unprotected sexual intercourse
  • maternal smoking
  • genitourinary infection.
  • low parity
  • low socio-economic status
  • poor maternal diet
  • drugs - decongestants, ibuprofen and aspirin (1,2)


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