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Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

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Hypersplenism is an imprecise term commonly used to refer to a clinical state characterised by:

  • reduced red blood cells, platelets, and granulocytes in any combination
  • splenomegaly of any cause
  • an adequately cellular bone marrow - ie. indicating that there is sufficient compensation to cytopenia
  • totally or partially correctable by splenectomy

Symptoms include:

  • abdominal discomfort
  • anaemia
  • infection
  • bleeding

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