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Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

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Macroglossia can occur in in a number of conditions, as follows:

  • Down's syndrome
  • Beckwith-Wiedemann syndrome
  • Hurler's syndrome
  • endocrine disturbances such as acromegaly or congenital hypothyroidism.
  • tumour infiltration, for example lymphangioma.
  • primary, or occasionally, secondary amyloidosis.

It is important to be aware of the relationship between macroglossia and micrognathia - the latter can give an impression of the former.

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