This site is intended for healthcare professionals
Last reviewed dd mmm yyyy. Last edited dd mmm yyyy
The majority (95%) are a squamous cell carcinoma. They are rare in the UK but are frequent in the Far East and African countries. The tumour arises from the inner surface of the foreskin or glans penis in the region of the coronal sulcus i.e. between glans and prepuce. It spreads locally and frequently invades the distal urethra. The inguinal lymph nodes are commonly involved, often bilaterally, but blood borne spread is rare and late.
The condition may start as leucoplakia on the glans or may develop from an in-situ carcinoma - erythroplasia of Queryat (1)
Carcinoma is rare in the circumcised (1).
1 in 493 UK males will be diagnosed with penile cancer in their lifetime (2)