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Platelet-derived growth factor

Authoring team

Platelet-derived growth factor is a peptide cytokine produced from:

  • platelets
  • mononuclear phagocytes
  • endothelial cells
  • epithelial cells

Its present known in vitro functions include:

  • increased phagocytosis
  • increased neutrophil oxidative killing
  • stimulation of the division of fibroblasts and smooth muscle cells
  • increased secretion of metalloproteinases with a role in tissue repair
  • stimulation of chemotaxis for monocytes and granulocytes

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The content herein is provided for informational purposes and does not replace the need to apply professional clinical judgement when diagnosing or treating any medical condition. A licensed medical practitioner should be consulted for diagnosis and treatment of any and all medical conditions.

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