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Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

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Bruxism is used to refer to grinding of the teeth.

It may be seen in a variety conditions which cause learning disabilities, particularly in Down's sydrome.

Drug-induced bruxism (1):

  • a review (564 reports of bruxism; 2000 to 2022) found an association with use of antidepressants (sertraline, escitalopram, venlafaxine, vortioxetine, citalopram, paroxetine, fluoxetine, duloxetine) and antipsychotics (ziprasidone, aripiprazole, olanzapine, risperidone)
  • a signal was also described for oxybate sodium and metoclopramide


  • Montastruc, J-L. Drugs and bruxism: a study in the World Health Organization’s pharmacovigilance database. Br J Clin Pharmacol. 2023. Accepted Author Manuscript.

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