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Malignant atrophic papulosis

Authoring team

Dego's disease is a rare, lethal condition affecting the skin, gut and nervous system.

Presentation:

  • skin lesions are pathognomonic - circular, porcelain- white, with a depressed centre (4 to 8mm diameter), and slightly elevated erythematous margin.
  • arterial lesion - endothelial swelling causing luminal stenosis. There may be fibrinoid necrosis of the wall of the lumen.

Death is generally as a result of intestinal perforation.

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