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Cryptococcal meningitis is usually a disease of the immunocompromised. It has become more common with the appeareance of AIDS.
Cryptococcus neoformans is the pathogenic fungus. It is a common organism found in the soil, particularly in bird droppings. The portal of entry is usually the lung.
The predominant clinical process is a variably subacute meningitis with occasional patients showing features of brain abscess or inflammatory cerebral vasculitis.