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Ep 50 – Post-sepsis syndrome


Posted 22 Jul 2022

Dr Kate Chesterman

In this podcast, Dr Kate Chesterman discusses post-sepsis syndrome. She talks about the long-term implications for physical and mental health following sepsis and highlights the considerations for primary care clinicians in managing this cohort of individuals. She also discusses the role of the wider multidisciplinary team, including input from voluntary organisations.


Key references discussed in the episode:

  1. UK Sepsis Trust. The Sepsis Manual (6th edition). 2022.
  2. Sangan V. Nursing Times. 2019;115:8,19-21.
  3. van der Slikke EC, et al. EBioMedicine. 2020 Nov;61:103044. doi: 10.1016/j.ebiom.2020.103044.

Patient information:

Key take-home points:

  • Post-sepsis syndrome is a collection of physical, cognitive and psychological symptoms that some patients may develop after sepsis.
  • These symptoms can persist for years after discharge and have a significant effect on a patient’s quality of life as well as increasing the risk of rehospitalisation and increasing mortality.
  • Patients have an increased risk of recurrent and new infections as well as cardiovascular and renal disease.
  • Organisations such as the UK Sepsis Trust can provide information and support to those recovering from sepsis and their loved ones.

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