congenital malformations of the limbs

Last reviewed 01/2018

Congenital malformations or anomalies in the production of limbs are usually the result of agents acting during the fourth to seventh weeks of pregnancy. The aetiology is largely unknown but a number of potential causes may result in a similar phenotype.

Major limb malformations are found in 2 in every 1000 neonates. They may be considered in terms of site of malformation.