cautions and contraindications

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Contraindications include:

  • moderate or severe renal impairment
  • impaired hepatic function
  • severe hypoproteinaemia
  • known immunodeficiency
  • bone marrow dysfunction, leucopenia, neutropenia, anaemia, thrombocytopenia - secondary to causes other than RA
  • serious infections
  • known hypersensitivity to leflunomide
  • women who are pregnant or who are breast feeding - after stopping treatment the manufacturer advises that a woman should wait for 2 years before trying to conceive
  • this drug has not been tested in people under 18 years old and therefore is contraindicated in patients below this age

Check the manufacturer's prescribing information before prescribing this drug.

Last reviewed 01/2018