pathophysiology

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Myocardial ischaemia is more likely to affect the left ventricle than the right ventricle, because:

  • the coronary blood supply of the left ventricle is confined to diastole. This is because of the high intramural pressure that occurs in systole that prevents a blood supply.
  • the stroke work that is required by the left ventricle is greater than that of the right ventricle. The systemic arterial resistance is 8x that of the pulmonary resistance.

Last reviewed 01/2018