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Prognosis

Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

Authoring team

Some information concerning the prognosis in mitral regurgitation is given below:

  • mild regurgitation:
    • prognosis is good
    • risk of infective endocarditis and rarely, chordal rupture in redundant prolapsed cusps
    • regurgitation tends to increase with age

  • severe regurgitation:
    • initially, well tolerated as there is little resistance to left ventricular outflow
    • with time left ventricular failure develops
    • contractility may appear good on echo due to the diminished afterload
    • if surgical repair is left too late, abolition of mitral regurgitation results in a sudden increase in afterload which may not be tolerated by a poor left ventricle

  • ischaemic regurgitation:
    • in the longterm the prognosis is of the underlying coronary disease

  • results from surgery:

  • mortality:
    • valve replacement 6%
    • valve repair 2%
    • increased in patients with left ventricular failure

  • paraprosthetic leak:
    • about 2%
    • higher in prolapsing valves

  • residual mitral regurgitation:
    • mitral valve repair 5%
    • reoperation rate in mitral valve repair of about 2%

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