clinical features

Last edited 08/2021 and last reviewed 08/2021

Patients are frequently asymptomatic.

In others, presentation may be with features such as:

  • mild hypertension
  • lethargy
  • muscular weakness
  • polyuria and polydipsia
  • persistent hypokalaemia
  • intermittent paraesthesiae, tetany and occasionally paralysis

There is an increasing frequency in the diagnosis of primary aldosteronism (1):

  • principal reason for the increasingly frequent diagnosis of this disease, once viewed as rare, is that normokalemic Conn's syndrome is now recognized as an independent disease entity
  • normal serum potassium may be present in up to 38% of patients, especially in patients with adrenal hyperplasia or familial aldosteronism
  • found in 5% to 18% of patients with high blood pressure


  • Aronova A, Fahey TJ III, Zarnegar R. Management of hypertension in primary aldosteronism. World J Cardiol. 2014 May 26;6(5):227-33