hyperchloraemic metabolic acidosis

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Normal anion gap / hyperchloraemic acidosis:

  • bicarbonate loss in the gut, e.g. pancreatic fistula, diarrhoea, utero-enterostomy

  • renal tubular acidosis:
    • proximal - bicarbonate loss
    • distal - failure of acidification - proton pump failure
    • treatment with excessive carbonic anhydrase inhibitors

Last reviewed 01/2018

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