This site is intended for healthcare professionals

Go to /sign-in page

You can view 5 more pages before signing in

High risk groups

Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

Authoring team

The following groups are at high risk of having coeliac disease:

  • first degree relatives - 5-11% chance of being affected
  • second degree relatives – around 2.5%
  • genetic susceptibility
    • genes encoding HLA DQ2
    • genes encoding HLA DQ8
  • other autoimmune conditions
    • insulin-dependent diabetes - approximately 2-4% are affected by coeliac disease.
    • autoimmune thyroid disease - approximately 2-4% are affected by coeliac disease.
  • increased incidence in patients with Down's syndrome.
  • selective IgA deficiency - approximately 10% are affected by coeliac disease

Reference:


Related pages

Create an account to add page annotations

Add information to this page that would be handy to have on hand during a consultation, such as a web address or phone number. This information will always be displayed when you visit this page