Hidradenitis suppurativa (also known as Verneuil's disease or acne inverse) is a deep-seated inflammatory condition that produces lesions which mainly occur in the axillae, groins and anogenital areas of the body (1).
Hidradenitis is primarily an acne-like follicular occlusion disease where apocrine glands only become involved in the context of peri-follicular inflammation - it is not a primary disease of apocrine glands (1,2).
The disease can be seen after puberty and most commonly in the second or third decade of life (2). This has lead to the hypothesis that hormones play a role in the pathogenesis of the disease (1).
Friction from axillary adiposity, sweat, heat, stress, tight clothing, genetic and hormonal components has been recognized as contributory factors (1).
- (1) Shah N. Hidradenitis Suppurativa: A Treatment Challenge. AFP 2005;72(8)
- (2) Sohail N et al. Photo Quiz Chronic, Draining Perianal Sinuses. AFP 2006;74(12)
Last reviewed 06/2021