Macroglossia can occur in in a number of conditions, as follows:
- Down's syndrome
- Beckwith-Wiedemann syndrome
- Hurler's syndrome
- endocrine disturbances such as acromegaly or congenital hypothyroidism.
- tumour infiltration, for example lymphangioma.
- primary, or occasionally, secondary amyloidosis.
It is important to be aware of the relationship between macroglossia and micrognathia - the latter can give an impression of the former.
Last reviewed 01/2018