polymyxin B

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Indications:-

  • bowel sterilisation in neutropenic patients
  • in some topical applications

Cautions:-

  • reduce dose in renal impairment
  • beware interactions - See current issue BNF

Contra-indications:-

  • myasthenia gravis

Side-effects:-

  • muscle weakness
  • apnoea
  • perioral and peripheral paraesthesia
  • vertigo
  • nephrotoxicity

Routes of administration:-

  • Slow i.v. infusion

Last reviewed 01/2018