FREE subscriptions for doctors and students... click here
You have 3 more open access pages.

Alanine aminotransferase is a cytoplasmic enzyme that is predominantly hepatic in origin. Therefore, changes tend to parallel those of aspartate aminotransferase, but ALT is more liver-specific.

Mild hepatic injury tends to increase the ratio of cytoplasmic ALT to AST; more severe disease reverses the trend.

Last reviewed 01/2018