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Gastrointestinal manifestations

Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

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GI disturbances are common in SLE patients and may be due to primary gastrointestinal disorders, complications of therapy or SLE itself (1).

GI manifestations in SLE include:

  • oral ulceration - is a common feature
  • nausea, vomiting, or anorexia occur in about 20% of cases
  • abdominal pain - may be due to active lupus, including peritonitis, pancreatitis, mesenteric vasculitis, and bowel infarction
  • jaundice - due to autoimmune hepatitis (1)
  • ascites is rare but often massive
  • hepatomegaly occurs in about 30% of cases
  • splenomegaly occurs in about 20% of cases and is unusually associated with haemolytic anaemia

Reference:

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