Panicinian Corpuscles are the terminal derivative of myelinated nerve fibres within connective tissue. Round in shape and relatively large structures, cross-section reveals an 'onion-like' structure of regular layers of cells divided by free fluid.
Displacement of the fluid is purported to be the means of transduction of external pressure stimuli into neuronal signals.
Panicinian Corpuscles are concentrated in areas of great sensitivity to external stimuli e.g. the dermis of the skin.
Last reviewed 01/2018