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General side-effects of centrally acting hypertensive agents

Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

Authoring team

Clonidine and methyldopa commonly cause side-effects including:

  • sedation and depression
  • dry mouth
  • oedema
  • rebound hypertension on discontinuing treatment

Sedation is equally common with moxonidine but other side-effects are significantly reduced.

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