Increased basophils (> 0.1 x 10^9/l) seen in:
- viral infections
- ulcerative colitis
- systemic mastocytosis
- myeloproliferative disorders:
- chronic myeloid leukaemia
- polycythaemia rubra vera
Basophilia does not characteristically occur in secondary polycythaemia.
Note that excessive basophilia in chronic myeloid leukaemia may indicate the transformation into an accelerated or 'blastic' phase.
Last reviewed 01/2018