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Pathogenesis

Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

Authoring team

The cholesterol emboli syndrome is seen in patients with generalised atherosclerosis. Vascular insults, thrombolysis or anticoagulation result in rupture of atheromatous plaques and release of cholesterol crystals into the blood.

Lodging of the crystals in a capillary bed results in:

  • distal necrosis
  • an inflammatory reaction resulting in eosinophilia

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