warfarin and antibiotics
The anticoagulant effect of warfarin and other coumarins is reduced by rifamycins.
Antibiotics that enhance the anticoagulant effect include:
There is possible enhancement of the anticoagulant effect by:
- nalidixic acid
There is anecdotal evidence that the INR can be altered following a course of oral broad spectrum antibiotic e.g. ampicillin.
Last reviewed 01/2022