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Diagnostic criteria

Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

Authoring team

A diagnosis of adult Still's disease requires five of the following criteria, including two or more major criteria:

  • major criteria:
    • fever of 39 deg.C.
    • arthralgia
    • typical rash
      • salmon-pink, maculopapular, evanescent, pruritic
    • neutrophil leukocytosis

þ minor criteria:

  • sore throat
  • lymphadenopathy +/- splenomegaly
  • liver dysfunction
  • negative rheumatoid factor and anti-nuclear factor

The serum ferritin level is usually grossly elevated.

Exclusions:

  • infection
  • malignancy
  • rheumatic disease

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