human herpesvirus 4
Epstein Barr virus (EBV) is a member of the herpes family.
It is the causative agent of infectious mononucleosis and has been implicated in the pathogenesis of various types of human tumour:
- Burkitt's lymphoma
- B-cell lymphomas in immunocompromised individuals
- undifferentiated nasopharyngeal carcinoma
- recent studies have identified other virus-associated malignancies, including Hodgkin's lymphoma, various T-cell lymphomas, and some carcinomas (undifferentiated carcinomas of the nasal type have been observed in the stomach, salivary glands, thymus and the lungs; although these tumours are not invariably associated with EBV)
Last reviewed 01/2018