a meta-analysis has concluded that low doses of vitamin B6 (pyridoxine) are likely to improve the symptoms of premenstrual syndrome (1)
there is no rationale for giving daily doses in excess of vitamin B6 in excess of 100mg.
the authors of the meta-analysis conclude that vitamin B6 is probably effective in relieving overall premenstrual syndrome and in relieving PMS depression (1)
pyridoxine can be suggested as a treatment for PMS, at least for the psychiatric symptoms (2)
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