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First described by Hippocrates, tetanus is a disease caused by Clostridium tetani, an organism that only flourishes in dead tissue and produces an exotoxin which passes to the central nervous system (1).

  • the toxin targets anterior horn cells and once fixed, it cannot be neutralized by antitoxin

The infection does not transmit from person to person and there is no herd immunity (3)

Tetanus is a notifiable disease in UK (2).


Last edited 11/2019