This site is intended for healthcare professionals

Go to /sign-in page

You can view 5 more pages before signing in

Cytotoxic drugs

Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

Authoring team

Two main cytotoxic agents are used, with steroids:

  • cyclophosphamide
  • azathioprine - less effective but used for it's steroid sparing effects in maintenance treatment. Dose 1.0-2.5 mg/kg/day; either started with steroids or added at a later date. Lymphoma is a feared side effect

Less commonly:

  • cyclosporin - high renal toxicity. Reserved for patients unresponsive to conventional immunosuppression or in whom marrow toxicity is a major problem

  • methrotrexate - long history of intermittent use

Related pages

Create an account to add page annotations

Add information to this page that would be handy to have on hand during a consultation, such as a web address or phone number. This information will always be displayed when you visit this page