revaccination of pneumococcal vaccine

Last edited 04/2019 and last reviewed 05/2019


  • reinforcing (booster) dose of PCV13 is recommended on or after the first birthday
  • vaccine is given at the same time as the Hib/MenC, 4CMenB and MMR vaccines


  • antibody levels are likely to decline rapidly in individuals with no spleen, splenic dysfunction or chronic renal disease - therefore re-immunisation with PPV23 is recommended every five years in these groups
  • revaccination is well tolerated
  • testing antibody levels prior to vaccination is not required
  • if estimated that pneumococcal vaccine protects against pnSee current BNF for more details


  • Pulse (2001), 61 (33), 48
  • The Green Book. Chapter 25 - Pneumococcal (April 2019)