vitamin E deficiency

Last reviewed 01/2018

Deficiency of vitamin E is rare in humans. It may cause the oxidation of unsaturated fats resulting in abnormal structure and function of mitochondria, lysosomes, and plasma membranes.

Clinically, deficiency is manifest as:

  • haemolytic anaemia and only partly
  • spinocerebellar degeneration, only partly reversible
  • peripheral neuropathy

Vitamin E deficiency also has an immunosuppressive effect, and results in muscular dystrophy in monkeys and sterility in rats.