LDH in miscellaneous conditions

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Plasma LDH may also be raised in:

  • liver disease - poor specifity
  • skeletal muscle disease e.g. muscular dystrophies
  • haemolysis, both in vitro and in vivo
  • leukaemia - to very high levels
  • pernicious anaemia - to very high levels
  • megaloblastic anaemia - very large elevation
  • myeloproliferative disorders
  • thalassaemia
  • malignancy of all types e.g. raised levels in pleural fluid relative to plasma are a key index of suspicion
  • renal infarction
  • pulmonary embolus
  • congestive cardiac failure
  • hypothyroidism

Last reviewed 01/2018

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